Journal article
K. Sommer, F. Schweser, A. Deistung, J. Reichenbach
2011
2011
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APA
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Sommer, K., Schweser, F., Deistung, A., & Reichenbach, J. (2011). Investigating non-susceptibility contributions to GRE phase contrast.
Chicago/Turabian
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Sommer, K., F. Schweser, A. Deistung, and J. Reichenbach. “Investigating Non-Susceptibility Contributions to GRE Phase Contrast” (2011).
MLA
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Sommer, K., et al. Investigating Non-Susceptibility Contributions to GRE Phase Contrast. 2011.
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@article{k2011a,
title = {Investigating non-susceptibility contributions to GRE phase contrast},
year = {2011},
author = {Sommer, K. and Schweser, F. and Deistung, A. and Reichenbach, J.}
}
Abstract
INTRODUCTION – Quantitative susceptibility mapping (QSM) is a novel imaging technique that determines tissue magnetic susceptibility from conventional gradientecho (GRE) phase images. While it has been shown that the main part of phase contrast can be explained by the bulk magnetic susceptibility (BMS) of tissue [1], the requirement for strong regularization during reconstruction indicates that non-BMS contributions are present in the phase images. This is confirmed by recent investigations that suggest that local non-BMS effects, such as chemical exchange between water and macromolecules [2] or a non-spherical Lorentzian cavity [3], contribute to phase contrast between gray and white matter. In this contribution, we present a technique for separating BMS and non-BMS effects in phase data and, as a proof-of-principle, demonstrate it with an initial experiment based on simulated data.